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Organic fluorides have very high chemical and thermal stability; their major uses are as refrigerants, electrical insulation and cookware, the last as PTFE (Teflon). "Some experiments and observations on the substances produced in different chemical processes on fluor spar".

Pharmaceuticals such as atorvastatin and fluoxetine also contain fluorine, and the fluoride ion inhibits dental cavities, and so finds use in toothpaste and water fluoridation.

Global fluorochemical sales amount to more than US billion a year.

Fluorocarbon gases are generally greenhouse gases with global-warming potentials 100 to 20,000 times that of carbon dioxide.

Only in 1886 did French chemist Henri Moissan isolate elemental fluorine using low-temperature electrolysis, a process still employed for modern production. "Solid State Molecular Structures of Transition Metal Hexafluorides".

F) contains most of the world's fluorine, its low mass fraction of 3.5% means that most of it is used as a phosphate. The main commercial mine on Greenland's west coast closed in 1987, and most cryolite is now synthesized. "Recommendations for Using Fluoride to Prevent and Control Dental Caries in the United States". Sir Humphry Davy proposed that this then-unknown substance be named fluorine from fluoric acid and the -ine suffix of other halogens. This word, with modifications, is used in most European languages; Greek, Russian, and some others (following Ampère's suggestion) use the name ftor or derivatives, from the Greek φθόριος (phthorios, destructive) . Plunkett while working on refrigerants at Kinetic, and its superlative chemical and thermal resistance lent it to accelerated commercialization and mass production by 1941. is as corrosive as fluorine, gaseous diffusion plants required special materials: nickel for membranes, fluoropolymers for seals, and liquid fluorocarbons as coolants and lubricants.

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